Direct flights from Knoxville McGhee Tyson Airport (TYS)

Knoxville McGhee Tyson Airport in Knoxville, United States has direct flights to 15 airports in 1 country, flown by 8 airlines. The longest is to Denver (DEN) at 1,866 km.

Direct flights from TYS by country

United States (15)

• ATL Atlanta · 245 km · ~50m · Air France, Alaska Airlines and ITA Airways +1
• CLT Charlotte · 284 km · ~50m · American Airlines
• ORD Chicago · 765 km · ~1h 25m · American Airlines and United Airlines
• DFW Dallas-Fort Worth · 1,239 km · ~2h · American Airlines
• DEN Denver · 1,866 km · ~2h 45m · Frontier Airlines and United Airlines
• FLL Fort Lauderdale · 1,143 km · ~1h 55m · Allegiant Air
• IAH Houston · 1,241 km · ~2h · United Airlines
• LGA New York · 1,041 km · ~1h 45m · American Airlines
• EWR Newark · 1,014 km · ~1h 45m · United Airlines
• PHL Philadelphia · 891 km · ~1h 35m · American Airlines
• PGD Punta Gorda · 1,007 km · ~1h 45m · Allegiant Air
• SFB Sanford · 824 km · ~1h 30m · Allegiant Air
• PIE St. Petersburg · 887 km · ~1h 35m · Allegiant Air
• DCA Washington · 702 km · ~1h 20m · American Airlines
• IAD Washington · 674 km · ~1h 20m · United Airlines

Airlines flying from TYS

Air France, Alaska Airlines, Allegiant Air, American Airlines, Frontier Airlines, ITA Airways, KLM, United Airlines

Going somewhere TYS doesn’t fly direct?

Wayfli finds the best one- and two-stop connections from Knoxville to any airport in the world. Pick a destination on the map.

Routes come from current airline fares, updated weekly (last update 9 November 2026), plus older schedule data for airports with few recent fares. “Direct” can include a few same-plane flights with a stop. Flight times are estimates from distance. Always check with the airline before booking.